Novel approaches to liver disease diagnosis and modeling

Clinical Manifestations and Diagnosis of Non-Alcoholic Fatty Liver Disease

Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic steatohepatitis (NASH) and cirrhosis in Iran. M...

Approaches to the Diagnosis of Liver Fibrosis

Liver transplantation: current status and novel approaches to liver replacement.

The major challenge currently facing liver transplantation is the performance of a greater number of liver transplants, which has been fueled by the large and growing disparity between the increasing number of qualified patients listed for transplantation and the relatively static number of available cadaver donor organs. In the past 2 years, approximately 4500 liver transplants have been perfo...

Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease

Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. The aim of this study is evaluation of relation be...

Tuberculosis: novel approaches to an old disease.

Tuberculosis (TB), one of the most ancient and deadly diseases of mankind, has ravaged human communities since the beginning of civilization, and still remains one of the most devastating infectious diseases in the 21 st century. The latest report released by the World Health Organization estimates that 1.45 million deaths each year are due to TB, with 9 million incident cases and 14 million pr...